On the basis of the available evidence, the Centers for Disease Control and Prevention (CDC) confirms that the Zika virus is a cause of microcephaly and possibly other serious brain anomalies. In a special report published in the New England Journal of Medicine, the authors checked the existing evidence against the seven Shepard’s Criteria for proof of teratogenicity in humans, concluding that a causal relationship does exist and calling for an intensification of the efforts toward the prevention of adverse outcomes caused by congenital Zika virus infection.
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