cancer Archives - Among Doctors

Colorectal Cancer Incidence in a Dramatic Increase in the US

Posted on March 3, 2017

A study published by the American Cancer Society found a steep increase in the rate of colorectal cancer rose in adults younger than age 55 years. Three in 10 colorectal cancer diagnoses occur in people of this age group. The authors call for considering early screening as the proportion of rectal cancer diagnosed in adults younger than age 55 years years has doubled in just two decades.

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Posted in Clinical Highlights cancer, colorectal cancer, incidence, rectal cancer, screening

Picks of the Week: Pokemon, the ice bucket challenge, and other frontiers in medicine

Posted on August 19, 2016

From the employment of Pokémon GO! in public health to new advancements in tackling ALS and inducing partial recovery in paraplegic patients, there have been plenty of noteworthy news and evidence updates shared on the Among Doctors network. Let’s have a look at some of them:

Pokemon GO! Pandemic or Prescription? The Public Health Perspective
Pokémon GO! shows how an alternative way of thinking & and a new era of solutions are need to tackle old (or not-so-old) problems.
NEK1 variants confer susceptibility to amyotrophic lateral sclerosis
Two summers after the Ice Bucket Challenge, new research is crediting part of the $115 million raised to helping to identify NEK1 as a new ALS-related gene.
Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients
Following 12 months of training with this paradigm, all eight patients experienced neurological improvements in somatic sensation and regained voluntary motor control in key muscles.
Guideline Update on Duration of Dual Antiplatelet Therapy for CAD
This guideline-focused update on dual antiplatelet therapy for patients with coronary artery disease.
Pioglitazone Prevents Diabetes in Insulin-Resistant Patients With Cerebrovascular Disease
Pioglitazone is the first medication shown to prevent both progression to diabetes and major cardiovascular events as prespecified outcomes in a single trial.
Florida investigation links four recent Zika cases to local mosquito-borne virus transmission
The Centers for Disease Control and Prevention (CDC) has been informed by the State of Florida that Zika virus infections in four people were likely caused by bites of local Aedes aegypti mosquitoes.
Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis
People who achieve total physical activity levels several times higher than the current recommended minimum level of 600 METs/week (as recommended by the WHO) have a significant reduction in the risk of the five diseases studied.
Reasons for Trying E-cigarettes and Risk of Continued Use
Regulatory strategies such as increasing cost or prohibiting e-cigarette use in certain places may be important for preventing continued use in youth.

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Image credit: CC BY-SA 2.0 iphonedigital

Posted in Picks of the week ALS, breast cancer, cancer, coronary artery disease, diabetes mellitus, ice bucket challenge, ischemic heart disease, pokemon, public health, smoking, Zika, Zika virus

Picks of the Week: Stomach cancer, fluconazole, and a few systematic reviews!

Posted on April 29, 2016

Sharing news within Among Doctors network is a way of appraising and curating evidence, contributing to the dissemination of knowledge with your trusted network. Let’s have a look at what news have been shared lately:

Diet, nutrition, physical activity and stomach cancer
The World Cancer Research Fund released a new report on stomach cancer linking for the first time drinking alcohol, eating processed meat and being overweight to an increased risk of developing stomach cancers.
FDA evaluating study examining use of oral fluconazole in pregnancy
FDA is evaluating the results of a Danish study that conclude there is a possible increased risk of miscarriage with the use of oral fluconazole for yeast infections.
Cochrane Systematic Review: A comparison of different antibiotic regimens for the treatment of infective endocarditis
Limited and very low quality evidence suggested that there were no conclusive differences between antibiotic regimens in terms of cure rates or other relevant clinical outcomes.
Association between anticholinergic medication and cognition, brain metabolism, and brain atrophy in cognitively normal older adults
Anticholinergic medication use was linked with risk for future progression to mild cognitive impairment or Alzheimer’s disease.
Cochrane Systematic Review: Mobile phone-based interventions for smoking cessation
The current evidence supports a beneficial impact of mobile phone-based smoking cessation interventions on six-month cessation outcomes.
Exposure to advertisements and electronic cigarette use among US middle and high school students
The odds of electronic cigarette use increased with greater exposure to electronic cigarette advertising, with Internet advertisements having the strongest effect.

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Posted in Picks of the week alzheimer's disease, antibiotics, anticholinergic medication, brain atrophy, cancer, cognition, electronic cigarettes, fluconazole, infective endocarditis, mHealth, pregnancy, smoking, smoking cessation, stomach cancer

Alcohol, processed meat and being overweight linked to stomach cancer, report says

Posted on April 28, 2016

The World Cancer Research Fund released a new report on stomach cancer. For the first time, drinking alcohol, eating processed meat and being overweight have been linked to an increased risk of developing stomach cancers. In particular:

There is strong evidence that consuming approximately three or more alcoholic drinks per day increases the risk of stomach cancer.
There is strong evidence that consuming foods preserved by salting increases the risk of stomach cancer. Research mainly relates to high-salt foods and salt-preserved foods, including pickled vegetables and salted or dried fish, as traditionally prepared in east Asia.
There is strong evidence that consuming processed meat increases the risk of stomach non-cardia cancer.
There is strong evidence that being overweight or obese increases the risk of stomach cardia cancer. Being overweight or obese was assessed by body mass index (BMI).

Read the report and comment the story on Among Doctors

Posted in Clinical Highlights alcohol, cancer, overweight, processed meat, stomach cancer

Coffee consumption associated with 26% lower risk of colorectal cancer

Posted on April 14, 2016

Regular coffee consumption may be inversely associated with risk of colorectal cancer in a dose–response manner. In this study published in the April issue of Cancer Epidemiology, Biomarkers & Prevention, coffee consumption was associated with 26% lower odds of developing colorectal cancer. The inverse association was also observed for decaffeinated coffee consumption alone and for boiled coffee

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Posted in Clinical Highlights cancer, coffee, colorectal cancer

Picks of the Week: New guidelines and safety warnings on opioids

Posted on March 24, 2016

Sharing news within a peer community, such as the Among Doctors network, is a way of socially curating knowledge. Whether you wish to post your own piece of news, a guideline or a recently published article, or just start a new discussion within your own private group, Among Doctors is the right place to do all of that. So let’s have a look at what news have been shared lately on our network by fellow colleagues:

CDC Guideline for Prescribing Opioids for Chronic Pain
This guideline provides recommendations for primary care clinicians who are prescribing opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care.
Opioid Pain Medicines: New Safety Warnings Added to Prescription Opioid Medications
FDA is warning about several safety issues with the entire class of opioid pain medicines. These safety risks are potentially harmful interactions with numerous other medications, problems with the adrenal glands, and decreased sex hormone levels. We are requiring changes to the labels of all opioid drugs to warn about these risks.
Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis
Over 10 years of follow-up, no significant differences were found between patients who underwent stenting and those who underwent endarterectomy with respect to the risk of periprocedural stroke, myocardial infarction, or death and subsequent ipsilateral stroke.
The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation
A novel biomarker-based risk score for predicting stroke in AF was successfully developed and internally validated in a large cohort of patients with AF and further externally validated in an independent AF cohort. The ABC-stroke score performed better than the presently used clinically based risk score and may provide improved decision support in AF.

Posted in Picks of the week atrial fibrillation, cancer, corticosteroids, end-of-life care, FDA, neck pain, opioid, pain, pneumonia, stroke

Picks of the Week: Cancer screening, white coats and more!

Posted on January 11, 2016

Dear colleagues, first of all we’d like to wish you all a very happy new year!

In this blog, we continue picking up the top news updates from those that fellow colleagues have shared on the Among Doctors network. As many of you have already experienced, with this feature we can all become editors by selecting and sharing interesting news with the rest of our network. If you haven’t used it yet, give it try and let us know your thoughts.

Now, back to the latest top news:

Effects of cancer screening on overall mortality overstated, says report
There is insufficient evidence to claim cancer screening saves lives, argue experts in a report published in The BMJ, who call for future studies to assess the impact of cancer screening on overall mortality rather than disease-specific mortality alone.
Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units
Universal decolonisation of patients in the ICU with once a day chlorhexidine baths and short-course nasal mupirocin could be a potential preventive strategy in male patients because it significantly decreases candiduria and any bacteriuria, but not for women.

Posted in Picks of the week allergy, cancer, community-acquired pneumonia, Picks of the week