Regular coffee consumption may be inversely associated with risk of colorectal cancer in a dose–response manner. In this study published in the April issue of Cancer Epidemiology, Biomarkers & Prevention, coffee consumption was associated with 26% lower odds of developing colorectal cancer. The inverse association was also observed for decaffeinated coffee consumption alone and for boiled coffee
Thirty-three researchers and clinicians point out the potential link of infection to Alzheimer’s disease (AD) in a recently published editorial. They refer to the “many studies, mainly on humans, implicating specific microbes in the elderly brain, notably herpes simplex virus type 1, Chlamydia pneumoniae, and several types of spirochaete, in the etiology of AD.” Despite the wide breadth of supportive evidence, the authors say that topic is often dismissed as controversial, and urge further research on the link of infectious agents to AD including trials of antimicrobial therapy.
On the occasion of World Health Day 2016, WHO issued a call for action on diabetes, drawing attention to the need to step up prevention and treatment of the disease. The first WHO Global report on diabetes demonstrates that the number of adults living with diabetes has almost quadrupled since 1980 to 422 million adults. Factors driving this dramatic rise include overweight and obesity. In 2012 alone diabetes caused 1.5 million deaths. Its complications can lead to heart attack, stroke, blindness, kidney failure and lower limb amputation.
Image credit: WHO / Eduardo Martino
The prevailing emphasis on long-acting contraception is somewhat misplaced. Women’s decisions about which methods to use are less impactful than their decisions about whether to use contraception at all. Policymakers and practitioners will have the largest effects on fertility outcomes if they can change the behavior of sexually active women who neglect to use birth control when they are not seeking pregnancy.
This week many news updates were shared by colleagues on the Among Doctors network. As many of you have already experienced, with this feature you can appraise and share new articles and evidence with the rest of your network. Why don’t you try it right away: share something interesting from the home page!
Let’s see the latest top news:
- Dietary Patterns and Fractures in Postmenopausal Women
Higher adherence to a Mediterranean diet is associated with a lower risk for hip fractures. These results support that a healthy dietary pattern may play a role in maintaining bone health in postmenopausal women.
- Avoidance of sun exposure as a risk factor for major causes of death
The longer life expectancy amongst women with active sun exposure habits was related to a decrease in CVD and noncancer/non-CVD mortality, causing the relative contribution of death due to cancer to increase.
- Economic Analysis of Prostate-Specific Antigen Screening and Selective Treatment Strategies
The study reports that if PSA screening is to be cost-effective, it should be used conservatively and in combination with conservative management for low-risk disease.
- Antidepressant use and risk of cardiovascular outcomes in people aged 20 to 64: cohort study using primary care database
This study found no evidence that selective serotonin reuptake inhibitors are associated with an increased risk of arrhythmia or stroke/transient ischaemic attack in people diagnosed as having depression between the ages of 20 to 64 or that citalopram is associated with a significantly increased risk of arrhythmia.
- Oral fluoroquinolone use and serious arrhythmia
Oral fluoroquinolone treatment was not associated with an increased risk of serious arrhythmia in the general adult populations of Denmark and Sweden, contrary to previous reports. However, the majority of fluoroquinolones were ciprofloxacin, and it is possible that the risk is with other less frequently used fluoroquinolone.
- Gradual Versus Abrupt Smoking Cessation
Quitting smoking abruptly is more likely to lead to lasting abstinence than cutting down first, even for smokers who initially prefer to quit by gradual reduction.
- Diagnosing Acute Heart Failure in the Emergency Department: A Systematic Review and Meta-analysis
Bedside lung US and echocardiography appear to the most useful tests for affirming the presence of acute heart failure while natriuretic peptides are valuable in excluding the diagnosis.
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Prostate-specific antigen (PSA) screening for prostate cancer is controversial. Experts have suggested more personalized or more conservative strategies to improve benefit-risk tradeoffs, but the value of these strategies—particularly when combined with increased conservative management for low-risk cases—is uncertain. A new study published on JAMA suggests that for PSA screening to be cost-effective, it needs to be used conservatively and ideally in combination with a conservative management approach for low-risk disease.
Today is World TB Day and WHO calls on governments, communities, civil society, and the private sector to “Unite to End TB”. WHO and partners are promoting dialogue and collaboration that unites individuals and communities in new ways to end the tuberculosis (TB) epidemic. 43 million lives were saved through effective diagnosis and treatment, 2000-2014, yet 480,000 people developed multidrug-resistant tuberculosis (MDR-TB) in the world in 2014.
Sharing news within a peer community, such as the Among Doctors network, is a way of socially curating knowledge. Whether you wish to post your own piece of news, a guideline or a recently published article, or just start a new discussion within your own private group, Among Doctors is the right place to do all of that. So let’s have a look at what news have been shared lately on our network by fellow colleagues:
- CDC Guideline for Prescribing Opioids for Chronic Pain
This guideline provides recommendations for primary care clinicians who are prescribing opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care.
- Opioid Pain Medicines: New Safety Warnings Added to Prescription Opioid Medications
FDA is warning about several safety issues with the entire class of opioid pain medicines. These safety risks are potentially harmful interactions with numerous other medications, problems with the adrenal glands, and decreased sex hormone levels. We are requiring changes to the labels of all opioid drugs to warn about these risks.
- Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis
Over 10 years of follow-up, no significant differences were found between patients who underwent stenting and those who underwent endarterectomy with respect to the risk of periprocedural stroke, myocardial infarction, or death and subsequent ipsilateral stroke.
- The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation
A novel biomarker-based risk score for predicting stroke in AF was successfully developed and internally validated in a large cohort of patients with AF and further externally validated in an independent AF cohort. The ABC-stroke score performed better than the presently used clinically based risk score and may provide improved decision support in AF.
The FDA is warning about several safety issues with the entire class of opioid pain medicines. See the FDA Drug Safety Communication for a complete listing. These safety risks are potentially harmful interactions with numerous other medications, problems with the adrenal glands, and decreased sex hormone levels.
A plethora of news were shared on the Among Doctors network last week by fellow physicians; a result of a community which starts to grow with members wishing to share what they have appraised. Primary care and mental health, asthma over diagnosis, updates on the Zika virus and a new report on eHealth from the European office of the WHO. Let’s see the latest top news:
- Getting Primary Care at the Psychiatrist’s Office
People with severe mental illnesses are more likely to die prematurely than those without, and it’s often from treatable chronic diseases—in part because many, don’t receive regular medical care.
- Overdiagnosis of asthma in children in primary care: a retrospective analysis
Overdiagnosis of childhood asthma is common in primary care, leading to unnecessary treatment, disease burden, and impact on quality of life. However, only in a small percentage of children is a diagnosis of asthma confirmed by lung function tests.
- From innovation to implementation – eHealth in the WHO European Region
A new report on e-Health in the WHO European Region reveals that tangible progress has been made, with clear benefits for many countries. In most Member States, it has become commonplace for technology to be used to deliver health services and public health improvements, such as electronic health records.
- Effects of Long-Term Low-Molecular-Weight Heparin on Fractures and Bone Density in Non-Pregnant Adults
Low-molecular-weight heparin (LMWH) for 3–6 months may not increase the risk of fractures, but longer exposure for up to 24 months may adversely affect bone mineral density (BMD). Clinicians should consider monitoring BMD in adults on long-term LMWH who are at increased risk of bone loss or fracture.